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pubmed-article:8442794pubmed:abstractTextPercutaneous umbilical blood sampling (PUBS) is increasingly utilized for cytogenetic assessment of the fetus. In the present study, outcome of 109 PUBS-derived fetal blood samples were analyzed according to mode of ascertainment: ultrasound-detected anatomic anomalies or intrauterine growth retardation (IUGR). Abnormal chromosome complements were found in 6 of 47 (12.8%) fetuses with anomalies but in only 1 of 62 (1.6%) fetuses with IUGR alone. Perinatal loss in fetuses with anatomic anomalies was 64.4%, compared with only 1.6% in fetuses with IUGR alone. Mode of patient ascertainment is an important factor that must be considered in determining procedure-related risks for PUBS.lld:pubmed
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pubmed-article:8442794pubmed:pagination27-9lld:pubmed
pubmed-article:8442794pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:8442794pubmed:articleTitleMode of ascertainment is critical in assessing safety of percutaneous umbilical blood sampling.lld:pubmed
pubmed-article:8442794pubmed:affiliationDepartment of Obstetrics and Gynecology, University of Tennessee, Memphis 38103-2896.lld:pubmed
pubmed-article:8442794pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8442794pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:8442794pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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