Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1977-4-25
pubmed:abstractText
Cortisol concentrations in amniotic fluid and maternal plasma were determined by a competitive protein-binding assay in 14 patients in the midtrimester of pregnancy before and after intra-amniotic administration of prostaglandin F2alpha. Samples were obtained at three-hour intervals until abortion or until the fetal heartbeat ceased. The mean plasma levels of cortisol increased from 324 +/- 173 ng. per milliliter at hour 0 to 524 +/- 272 ng. per milliliter at 6 hours (the peak elevated value). In amniotic fluid, the mean levels of cortisol increased from 4.71 +/- 2.5 ng. per milliliter to a maximum at 9 hours of 10.24 +/- 2.5 ng. per milliliter. We concluded that at 16 to 20 weeks' gestation the fetoplacental unit is capable of responding to prostaglandin F2alpha instillation by increased levels of cortisol in the amniotic fluid.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0002-9378
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
127
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
629-42
pubmed:dateRevised
2007-8-20
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Cortisol levels in amniotic fluid in prostaglandin F2alpha-induced midtrimester abortion.
pubmed:publicationType
Journal Article