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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1977-4-15
|
| pubmed:abstractText |
To determine quantitatively characteristics of sleep-wakefulness rhythms in male albino rats, computer analysis of long term polygraphic records (24 h/day) of cortical EEG activity, neck EMG and EOG taken from 23 rats under 12:12 light-dark schedule was performed. After bilateral suprachiasmatic nucleus (SCN) lesions, the circadian rhythm in sleep-wakefulness was completely eliminated, although no attenuation or even slight enhancement of the ultradian rhythms with 2-4 h pweiodicity was observed. After enucleation of both eyes, the circadian rhythm was free-running with a phase shift in the range from --12 to +22 min/day in 6 rats. A gradual decrease of the spectral value of the circadian rhythm and inverse enhancement of the ultradian rhythms with 4--7 h periodicity (predominantly 6 h in 4 out of 6 rats) were also shown. In the spectral diagram, the appearance of paradoxical sleep (PS) paralleled slow-wave sleep (SWS), in the cases of the circadian rhythm and ultradian rhythms with 4--7 h periodicity. Behaviorally blind rats with bilateral primary optic tract (POT) lesions maintained the circadian rhythm in sleep-wakefulness entrained to the environmental light-dark cycle. Power spectral analysis showed no characteristic difference from normal rats. Based on these data, the role of the SCN as a pacemaker of endogenous circadian rhythm in sleep-wakefulness is discussed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0006-8993
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
11
|
| pubmed:volume |
122
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
33-47
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:837222-Animals,
pubmed-meshheading:837222-Circadian Rhythm,
pubmed-meshheading:837222-Hypothalamus,
pubmed-meshheading:837222-Male,
pubmed-meshheading:837222-Ocular Physiological Phenomena,
pubmed-meshheading:837222-Optic Nerve,
pubmed-meshheading:837222-Rats,
pubmed-meshheading:837222-Sleep,
pubmed-meshheading:837222-Sleep Stages,
pubmed-meshheading:837222-Supraoptic Nucleus,
pubmed-meshheading:837222-Wakefulness
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Analysis of sleep-wakefulness rhythms in male rats after suprachiasmatic nucleus lesions and ocular enucleation.
|
| pubmed:publicationType |
Journal Article
|