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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-8-23
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pubmed:abstractText |
This study assessed the efficacy of oral josamycin 1 g bd for five days as treatment for non-severe, community-acquired pneumonia in patients less than 60 years of age who were not at obvious risk of developing respiratory tract infection caused by aerobic Gram-negative bacilli. Of the 84 patients (43 male, 41 female) with a mean age of 33 years who were enrolled during a 14-month period, the clinical outcome was invariably favourable. All patients became afebrile within three days of starting therapy; the mean duration of fever after initiating treatment was 1.7 days. Therefore, according to the study protocol, josamycin therapy was discontinued on day five. A chest X-ray performed four to six weeks after completing treatment was normal in every case and no relapses were observed during a six-week follow-up period. We conclude that a five-day course of josamycin is effective monotherapy for community-acquired pneumonia in patients without the clinical features of severe infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0305-7453
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
749-54
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8335502-Adolescent,
pubmed-meshheading:8335502-Adult,
pubmed-meshheading:8335502-Female,
pubmed-meshheading:8335502-Humans,
pubmed-meshheading:8335502-Josamycin,
pubmed-meshheading:8335502-Legionnaires' Disease,
pubmed-meshheading:8335502-Male,
pubmed-meshheading:8335502-Middle Aged,
pubmed-meshheading:8335502-Pneumonia,
pubmed-meshheading:8335502-Pneumonia, Pneumococcal,
pubmed-meshheading:8335502-Pneumonia, Staphylococcal,
pubmed-meshheading:8335502-Q Fever,
pubmed-meshheading:8335502-Recurrence
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pubmed:year |
1993
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pubmed:articleTitle |
Five-day treatment of non-severe, community-acquired pneumonia with josamycin.
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pubmed:affiliation |
Infectious Diseases Unit, Hospital Clinic, University of Barcelona, Spain.
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pubmed:publicationType |
Journal Article
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