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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3 Pt 1
pubmed:dateCreated
1993-8-26
pubmed:abstractText
The incidence of spontaneous echo contrast in the left atrium, the factors with which it is associated, and its clinical significance were studied in 128 patients with native mitral valve disease or mitral valve replacement. All patients underwent both transesophageal and transthoracic echocardiography. Spontaneous echo contrast was visualized in 42 patients (33%) during transesophageal and in none during transthoracic echocardiography. Patients with spontaneous echo contrast had a significantly larger left atrial diameter (6.1 [1.1] cm vs 4.9 [0.9] cm, p < 0.001) and a greater incidence of both atrial fibrillation (54% vs 4%, p < 0.001) and left atrial thrombi (60% vs 28%, p < 0.01) compared with patients without spontaneous echo contrast. Multivariant analysis confirmed that these factors were independently associated with spontaneous echo contrast (left atrial size, p < 0.001; atrial fibrillation, p < 0.001; left atrial thrombus, p < 0.01). Patients with pure mitral regurgitation did not have any spontaneous echo contrast and anticoagulation did not influence its incidence. Spontaneous echo contrast was the only factor that was associated with a previous history of systemic embolization (history of systemic emboli in 28.6% of patients with spontaneous echo contrast vs 13.9% without spontaneous echo contrast, p < 0.05). In conclusion, spontaneous echo contrast is a common finding in the left atrium of patients with mitral valve disease or mitral valve replacement and represents a marker of increased thromboembolic risk in these patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0894-7317
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
299-307
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:8333979-Adult, pubmed-meshheading:8333979-Aged, pubmed-meshheading:8333979-Aged, 80 and over, pubmed-meshheading:8333979-Atrial Fibrillation, pubmed-meshheading:8333979-Echocardiography, pubmed-meshheading:8333979-Embolism, pubmed-meshheading:8333979-Endocarditis, pubmed-meshheading:8333979-Female, pubmed-meshheading:8333979-Heart Atria, pubmed-meshheading:8333979-Heart Valve Diseases, pubmed-meshheading:8333979-Heart Valve Prosthesis, pubmed-meshheading:8333979-Humans, pubmed-meshheading:8333979-Male, pubmed-meshheading:8333979-Middle Aged, pubmed-meshheading:8333979-Mitral Valve, pubmed-meshheading:8333979-Mitral Valve Insufficiency, pubmed-meshheading:8333979-Mitral Valve Prolapse, pubmed-meshheading:8333979-Mitral Valve Stenosis, pubmed-meshheading:8333979-Prospective Studies
pubmed:articleTitle
Left atrial spontaneous echo contrast assessed by TEE in patients with either native mitral valve disease or mitral valve replacement.
pubmed:affiliation
Department of Cardiology, King's College Hospital, London, UK.
pubmed:publicationType
Journal Article