Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:8309811rdf:typepubmed:Citationlld:pubmed
pubmed-article:8309811lifeskim:mentionsumls-concept:C0087111lld:lifeskim
pubmed-article:8309811lifeskim:mentionsumls-concept:C0028768lld:lifeskim
pubmed-article:8309811lifeskim:mentionsumls-concept:C0033929lld:lifeskim
pubmed-article:8309811lifeskim:mentionsumls-concept:C0699748lld:lifeskim
pubmed-article:8309811pubmed:issue4lld:pubmed
pubmed-article:8309811pubmed:dateCreated1994-3-11lld:pubmed
pubmed-article:8309811pubmed:abstractTextRecent advances in the pharmacotherapy of obsessive compulsive disorder (OCD) have led to a significant reduction in suffering and a return to productive living for many patients previously considered refractory to treatment. Potent inhibitors of 5-hydroxytryptamine (5-HT) re-uptake clearly have been established as the first-line pharmacotherapy for treatment of OCD. The addition of agents that enhance 5-HT neurotransmission to ongoing treatment in patients whose OCD is refractory to 5-HT re-uptake inhibitors has not yielded impressive results. The addition of dopamine (DA) antagonists to the regimens of treatment-resistant patients appears to be a potentially useful strategy for the specific subgroup of OCD patients with a comorbid chronic tic disorder such as Tourette's syndrome. Pharmacologic studies suggest that both the 5-HT and DA systems may be critical to the treatment and possibly the pathophysiology of OCD.lld:pubmed
pubmed-article:8309811pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8309811pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8309811pubmed:languageenglld:pubmed
pubmed-article:8309811pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8309811pubmed:citationSubsetIMlld:pubmed
pubmed-article:8309811pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8309811pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:8309811pubmed:statusMEDLINElld:pubmed
pubmed-article:8309811pubmed:monthDeclld:pubmed
pubmed-article:8309811pubmed:issn0193-953Xlld:pubmed
pubmed-article:8309811pubmed:authorpubmed-author:LeckmanJ FJFlld:pubmed
pubmed-article:8309811pubmed:authorpubmed-author:PriceL HLHlld:pubmed
pubmed-article:8309811pubmed:authorpubmed-author:McDougleC JCJlld:pubmed
pubmed-article:8309811pubmed:authorpubmed-author:GoodmanW KWKlld:pubmed
pubmed-article:8309811pubmed:issnTypePrintlld:pubmed
pubmed-article:8309811pubmed:volume16lld:pubmed
pubmed-article:8309811pubmed:ownerNLMlld:pubmed
pubmed-article:8309811pubmed:authorsCompleteYlld:pubmed
pubmed-article:8309811pubmed:pagination749-66lld:pubmed
pubmed-article:8309811pubmed:dateRevised2007-11-14lld:pubmed
pubmed-article:8309811pubmed:meshHeadingpubmed-meshheading:8309811-...lld:pubmed
pubmed-article:8309811pubmed:meshHeadingpubmed-meshheading:8309811-...lld:pubmed
pubmed-article:8309811pubmed:meshHeadingpubmed-meshheading:8309811-...lld:pubmed
pubmed-article:8309811pubmed:meshHeadingpubmed-meshheading:8309811-...lld:pubmed
pubmed-article:8309811pubmed:meshHeadingpubmed-meshheading:8309811-...lld:pubmed
pubmed-article:8309811pubmed:meshHeadingpubmed-meshheading:8309811-...lld:pubmed
pubmed-article:8309811pubmed:meshHeadingpubmed-meshheading:8309811-...lld:pubmed
pubmed-article:8309811pubmed:meshHeadingpubmed-meshheading:8309811-...lld:pubmed
pubmed-article:8309811pubmed:meshHeadingpubmed-meshheading:8309811-...lld:pubmed
pubmed-article:8309811pubmed:year1993lld:pubmed
pubmed-article:8309811pubmed:articleTitleThe psychopharmacology of obsessive compulsive disorder. Implications for treatment and pathogenesis.lld:pubmed
pubmed-article:8309811pubmed:affiliationDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.lld:pubmed
pubmed-article:8309811pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8309811pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:8309811pubmed:publicationTypeReviewlld:pubmed
pubmed-article:8309811pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8309811lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8309811lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8309811lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:8309811lld:pubmed