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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3 Suppl
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pubmed:dateCreated |
1994-3-14
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pubmed:abstractText |
Radioimmunotherapy of nude mice bearing human tumor xenografts using 90Y-labeled monoclonal antibodies has resulted in slower tumor growth, decreased tumor burden, and increased survival times. Dosimetry estimates in the murine model usually were based on biodistribution data and standard Medical Internal Radiation Dose approaches. A new dosimetric model for the mouse that takes into consideration the small dimensions, mass, and proximity of murine organs has been developed based on self-organ absorbed and cross-organ doses.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
958-65
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:8306285-Animals,
pubmed-meshheading:8306285-Antibodies, Monoclonal,
pubmed-meshheading:8306285-Beta Particles,
pubmed-meshheading:8306285-Carcinoembryonic Antigen,
pubmed-meshheading:8306285-Humans,
pubmed-meshheading:8306285-Immunotoxins,
pubmed-meshheading:8306285-Mice,
pubmed-meshheading:8306285-Mice, Inbred BALB C,
pubmed-meshheading:8306285-Neoplasm Transplantation,
pubmed-meshheading:8306285-Radioimmunotherapy,
pubmed-meshheading:8306285-Radiotherapy Dosage,
pubmed-meshheading:8306285-Transplantation, Heterologous,
pubmed-meshheading:8306285-Yttrium Radioisotopes
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pubmed:year |
1994
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pubmed:articleTitle |
Application of the cross-organ beta dose method for tissue dosimetry in tumor-bearing mice treated with a 90Y-labeled immunoconjugate.
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pubmed:affiliation |
Division of General and Oncologic Surgery, City of Hope National Medical Centre, Duarte, California.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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