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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1994-3-7
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pubmed:abstractText |
To determine the effects of glucocorticoid treatment on the microfilament structure of cultured human trabecular meshwork cells. Topical or systemic administration of glucocorticoids can lead to the development of ocular hypertension and to the development of vision loss, which is clinically similar to primary open angle glaucoma. However, the mechanism(s) by which glucocorticoids cause ocular hypertension is not well defined. Alterations in the trabecular meshwork, the site of drainage of aqueous humor from the eye, have been linked to the development of ocular hypertension.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0146-0404
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
281-94
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8300356-Actin Cytoskeleton,
pubmed-meshheading:8300356-Actins,
pubmed-meshheading:8300356-Adolescent,
pubmed-meshheading:8300356-Adult,
pubmed-meshheading:8300356-Aged,
pubmed-meshheading:8300356-Aged, 80 and over,
pubmed-meshheading:8300356-Cell Division,
pubmed-meshheading:8300356-Cell Movement,
pubmed-meshheading:8300356-Cells, Cultured,
pubmed-meshheading:8300356-Cross-Linking Reagents,
pubmed-meshheading:8300356-Dose-Response Relationship, Drug,
pubmed-meshheading:8300356-Glucocorticoids,
pubmed-meshheading:8300356-Humans,
pubmed-meshheading:8300356-Microscopy, Fluorescence,
pubmed-meshheading:8300356-Middle Aged,
pubmed-meshheading:8300356-Phalloidine,
pubmed-meshheading:8300356-Rhodamines,
pubmed-meshheading:8300356-Trabecular Meshwork
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pubmed:year |
1994
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pubmed:articleTitle |
Glucocorticoid-induced formation of cross-linked actin networks in cultured human trabecular meshwork cells.
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pubmed:affiliation |
Alcon Laboratories, Inc., Fort Worth, Texas 76134.
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pubmed:publicationType |
Journal Article,
Comparative Study
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