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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1994-2-10
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pubmed:abstractText |
HLA expression is frequently altered in tumours compared to the tissue from which they originate. Given the central role of MHC products in the restriction of T-cell recognition, regulation of tumour HLA expression might be a strategy for the evasion of immune surveillance by the malignant cells. Federico Garrido, Peter Stern and colleagues present data from a variety of tumour types, suggesting that HLA class I alterations may occur at a particular step between the development of an in situ lesion and an invasive carcinoma.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
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pubmed:issn |
0167-5699
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
14
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
491-9
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8274189-Carcinoma in Situ,
pubmed-meshheading:8274189-Female,
pubmed-meshheading:8274189-Gene Expression,
pubmed-meshheading:8274189-HLA Antigens,
pubmed-meshheading:8274189-Humans,
pubmed-meshheading:8274189-Models, Biological,
pubmed-meshheading:8274189-Neoplasm Invasiveness,
pubmed-meshheading:8274189-Neoplasms,
pubmed-meshheading:8274189-Precancerous Conditions
|
pubmed:year |
1993
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pubmed:articleTitle |
Natural history of HLA expression during tumour development.
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pubmed:affiliation |
Dept of Analisis Clínicos e Immunología, Hospital Virgen de las Nieves, Universidad de Granada, Spain.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|