| pubmed-article:8240339 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8240339 | lifeskim:mentions | umls-concept:C0027950 | lld:lifeskim |
| pubmed-article:8240339 | lifeskim:mentions | umls-concept:C0007625 | lld:lifeskim |
| pubmed-article:8240339 | lifeskim:mentions | umls-concept:C0057256 | lld:lifeskim |
| pubmed-article:8240339 | lifeskim:mentions | umls-concept:C0068355 | lld:lifeskim |
| pubmed-article:8240339 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:8240339 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8240339 | pubmed:dateCreated | 1993-12-9 | lld:pubmed |
| pubmed-article:8240339 | pubmed:abstractText | HNP-1 [correction of NHP-1], a member of a family of microbicidal cationic, cystine-rich polypeptides abundant in the azurophilic granules of polymorphonuclear leukocytes (PMN) interfered with detergent-induced cell-free activation of superoxide-producing NADPH oxidase. IC50 of 3 microM has been evaluated for this dose dependent effect of defensin. Preactivated oxidase was not affected by HNP-1. The inhibitory effect could be relieved by raising the concentration of the cytosol or by the addition of a partially purified p47-phox. NADPH oxidase activated in the presence of HNP-1 exhibited an increased affinity for NADPH. | lld:pubmed |
| pubmed-article:8240339 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8240339 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8240339 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8240339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8240339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8240339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8240339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8240339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8240339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8240339 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8240339 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8240339 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:8240339 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:8240339 | pubmed:author | pubmed-author:AviramII | lld:pubmed |
| pubmed-article:8240339 | pubmed:author | pubmed-author:TalTT | lld:pubmed |
| pubmed-article:8240339 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8240339 | pubmed:day | 29 | lld:pubmed |
| pubmed-article:8240339 | pubmed:volume | 196 | lld:pubmed |
| pubmed-article:8240339 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8240339 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8240339 | pubmed:pagination | 636-41 | lld:pubmed |
| pubmed-article:8240339 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8240339 | pubmed:meshHeading | pubmed-meshheading:8240339-... | lld:pubmed |
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| pubmed-article:8240339 | pubmed:meshHeading | pubmed-meshheading:8240339-... | lld:pubmed |
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| pubmed-article:8240339 | pubmed:meshHeading | pubmed-meshheading:8240339-... | lld:pubmed |
| pubmed-article:8240339 | pubmed:meshHeading | pubmed-meshheading:8240339-... | lld:pubmed |
| pubmed-article:8240339 | pubmed:meshHeading | pubmed-meshheading:8240339-... | lld:pubmed |
| pubmed-article:8240339 | pubmed:meshHeading | pubmed-meshheading:8240339-... | lld:pubmed |
| pubmed-article:8240339 | pubmed:meshHeading | pubmed-meshheading:8240339-... | lld:pubmed |
| pubmed-article:8240339 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8240339 | pubmed:articleTitle | Defensin interferes with the activation of neutrophil NADPH oxidase in a cell-free system. | lld:pubmed |
| pubmed-article:8240339 | pubmed:affiliation | Department of Biochemistry, Faculty of Life Sciences, Tel-Aviv University, Israel. | lld:pubmed |
| pubmed-article:8240339 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8240339 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8240339 | lld:pubmed |
