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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1994-6-9
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pubmed:abstractText |
The relationship between exposure to 1,2,4-trimethylbenzene (1,2,4-TMB) and urinary concentration of 3,4-dimethylhippuric acid (3,4-DMHA), one of its metabolites, was studied in workers involved in transfer printing. Airborne TMBs were sampled by an organic vapor monitoring badge and analyzed by capillary gas chromatography. Urinary 3,4-DMHA and creatinine were analyzed under the same conditions of high-performance liquid chromatography. The exposure concentration of 1,2,4-TMB among workers was around 25 ppm, the threshold limit value (TLV). The urinary concentration of 3,4-DMHA was low at the start of each shift and high at the end. Exposure to the TLV (25 ppm) of 1,2,4-TMB results in a urinary 3,4-DMHA concentration of 410 mg/g creatinine (r = 0.897, P < 0.001). Urinary 3,4-DMHA concentration could be used as a biological monitoring index for 1,2,4-TMB exposure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3,4-dimethylhippuric acid,
http://linkedlifedata.com/resource/pubmed/chemical/Air Pollutants, Occupational,
http://linkedlifedata.com/resource/pubmed/chemical/Benzene Derivatives,
http://linkedlifedata.com/resource/pubmed/chemical/Hippurates,
http://linkedlifedata.com/resource/pubmed/chemical/pseudocumene
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pubmed:status |
MEDLINE
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pubmed:issn |
0340-0131
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
295-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8175183-Adult,
pubmed-meshheading:8175183-Air Pollutants, Occupational,
pubmed-meshheading:8175183-Benzene Derivatives,
pubmed-meshheading:8175183-Environmental Monitoring,
pubmed-meshheading:8175183-Hippurates,
pubmed-meshheading:8175183-Humans,
pubmed-meshheading:8175183-Male,
pubmed-meshheading:8175183-Maximum Allowable Concentration,
pubmed-meshheading:8175183-Middle Aged,
pubmed-meshheading:8175183-Occupational Diseases,
pubmed-meshheading:8175183-Occupational Exposure,
pubmed-meshheading:8175183-Printing
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pubmed:year |
1994
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pubmed:articleTitle |
Determination of 3,4-dimethylhippuric acid as a biological monitoring index for trimethylbenzene exposure in transfer printing workers.
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pubmed:affiliation |
Department of Public Health, Nagoya City University Medical School, Japan.
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pubmed:publicationType |
Journal Article
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