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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1994-5-6
|
| pubmed:abstractText |
Assessed longitudinally the effects of HIV infection and zidovudine on the adaptive behavior of 25 children with symptomatic disease (M age = 5.3 years; range = 1-12; 52% classified as encephalopathic) by parent report using the Vineland Adaptive Behavior Scales. Patients also were evaluated with an age-appropriate intelligence test and Q-sort Behavioral Rating Scale. Before treatment, encephalopathic children exhibited greater impairments in adaptive behavior than those without encephalopathy. After 6 months of zidovudine, all behavioral domains (communication, daily living, socialization) except for motor skills showed overall significant improvement. Children with or without encephalopathy showed a similar degree of change. Improvements in adaptive behavior correlated with increases in cognitive ability and decreases in severity of aberrant social-emotional behavior.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0146-8693
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
19
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
47-61
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8151495-AIDS Dementia Complex,
pubmed-meshheading:8151495-Activities of Daily Living,
pubmed-meshheading:8151495-Child,
pubmed-meshheading:8151495-Child, Preschool,
pubmed-meshheading:8151495-Communication,
pubmed-meshheading:8151495-Female,
pubmed-meshheading:8151495-Follow-Up Studies,
pubmed-meshheading:8151495-HIV Infections,
pubmed-meshheading:8151495-Humans,
pubmed-meshheading:8151495-Infant,
pubmed-meshheading:8151495-Longitudinal Studies,
pubmed-meshheading:8151495-Male,
pubmed-meshheading:8151495-Motivation,
pubmed-meshheading:8151495-Q-Sort,
pubmed-meshheading:8151495-Quality of Life,
pubmed-meshheading:8151495-Social Behavior,
pubmed-meshheading:8151495-Socialization,
pubmed-meshheading:8151495-Zidovudine
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Adaptive behavior of children with symptomatic HIV infection before and after zidovudine therapy.
|
| pubmed:affiliation |
Pediatric Branch, National Cancer Institute, Bethesda, Maryland 20892.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|