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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1994-10-13
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pubmed:abstractText |
Gastrointestinal autonomic nerve (GAN) tumors, also known as plexosarcomas, are a rare distinct subtype of the gastrointestinal stromal tumors. These tumors are usually histologically low-grade, epithelioid or spindle-cell neoplasms that can be distinguished from the other gastrointestinal stromal tumors on the basis of their unique ultrastructural features. A 66-year-old female presented with a histologically high-grade sarcoma of the small bowel. Ultrastructural studies showed features of a GAN tumor. The light microscopic and ultrastructural features are described. The tumor cells gave strong, diffuse staining for vimentin and synaptophysin, and weak focal staining for neuron-specific enolase and S100. While usually presenting as low-grade neoplasms on histologic examination, this case demonstrates that GAN tumors should be considered in the differential diagnosis of a histologically high-grade sarcoma of the gastrointestinal tract, especially when evidence of smooth muscle, peripheral nerve sheath, or neuroblastic origin is not forthcoming.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0163-2116
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2051-5
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:8082518-Aged,
pubmed-meshheading:8082518-Autonomic Nervous System,
pubmed-meshheading:8082518-Female,
pubmed-meshheading:8082518-Humans,
pubmed-meshheading:8082518-Ileal Neoplasms,
pubmed-meshheading:8082518-Immunohistochemistry,
pubmed-meshheading:8082518-Liver Neoplasms,
pubmed-meshheading:8082518-Neoplasms, Nerve Tissue,
pubmed-meshheading:8082518-Sarcoma,
pubmed-meshheading:8082518-Synaptophysin,
pubmed-meshheading:8082518-Vimentin
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pubmed:year |
1994
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pubmed:articleTitle |
Gastrointestinal autonomic nerve tumor presenting as high-grade sarcoma. Case report and review of the literature.
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pubmed:affiliation |
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock 72205.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
|