Linked Life Data

8077766

Source:http://linkedlifedata.com/resource/pubmed/id/8077766

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-9-30
pubmed:abstractText
The antiviral and antiproliferative activities of human interferon-omega (IFN-omega) on two human cell lines and on VERO (monkey), MDBK (calf), SPEV (pig), L929 (mouse), BHK-21 (hamster), and MDCK (dog) cell lines were compared with those of human IFN-alpha 1 and IFN-alpha 2. The results are tabulated. Compared with its antiviral titer on human A549 cells, INF-omega was more active on mouse cells and even more active on the pig cells, but had little activity on the hamster cells and virtually none on the dog cells. IFN-omega also inhibited the growth of all these cells to a greater or lesser extent, and there was in general an apparent correlation between its antiviral and antiproliferative activities on the different cells, except that the dog cells were relatively much more sensitive to the antiproliferative effect.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0197-8357
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Cross-species antiviral and antiproliferative activity of human interferon-omega.
pubmed:affiliation
Institute of Virology, Slovak Acadmey of Sciences, Bratislava.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't