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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1994-8-25
|
| pubmed:abstractText |
We have studied the survival of 49 patients suffering from neuromuscular disease, who were hospitalised in the Respiratory Intensive Care Unit between 1981 and 1990 (29 males and 20 females with a mean age of 49.3 +/- 17 years with a range of 15 to 79). The neuromuscular diseases consisted of 8 with multiple sclerosis, 9 with amyotrophic lateral sclerosis, 8 with Steinert's disease, 11 myopathies, and 10 suffering from miscellaneous neurological diseases. Initially 27 of the 49 patients had been intubated and ventilated. During the hospital stay long-term ventilation was undertaken in 27 patients (21 by tracheotomy and 6 by nasal mask). The principal prognostic factor was the aetiology. Three groups of varying degrees of severity could be individualized: progressive neuromuscular disease (amyotrophic lateral sclerosis and multiple sclerosis), primary muscle disorders (myopathies and Steinert's disease), and neuromuscular disease with little or no evolution (survival at two years was 15%, 45% and 71% respectively for three groups. p = 0.001 by log-rank testing). The other factors which influence survival are age (p < 0.01), the presence of false route (p < 0.01), and the reason for hospitalisation (acute as opposed to chronic progressive deterioration, p < 0.05). In a multivariate analysis the most significant factors associated with the diagnosis were age, the reason for hospitalisation, and the existence of false routes. The initial treatment (intubation) and the prescription of long-term ventilation did not bring with it any significant further information as to prognosis, compared to the model which included these four factors.
|
| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0761-8425
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
11
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
263-70
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8041989-Acute Disease,
pubmed-meshheading:8041989-Adolescent,
pubmed-meshheading:8041989-Adult,
pubmed-meshheading:8041989-Aged,
pubmed-meshheading:8041989-Chronic Disease,
pubmed-meshheading:8041989-Female,
pubmed-meshheading:8041989-Humans,
pubmed-meshheading:8041989-Intensive Care Units,
pubmed-meshheading:8041989-Length of Stay,
pubmed-meshheading:8041989-Male,
pubmed-meshheading:8041989-Middle Aged,
pubmed-meshheading:8041989-Neuromuscular Diseases,
pubmed-meshheading:8041989-Prognosis,
pubmed-meshheading:8041989-Proportional Hazards Models,
pubmed-meshheading:8041989-Respiration, Artificial,
pubmed-meshheading:8041989-Respiratory Insufficiency,
pubmed-meshheading:8041989-Retrospective Studies,
pubmed-meshheading:8041989-Risk Factors,
pubmed-meshheading:8041989-Survival Rate
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
[Prognostic factors in the survival of patients with neuromuscular diseases after an episode of acute respiratory insufficiency].
|
| pubmed:affiliation |
Unité de Soins Intensifs, Hôpital G. & R. Laennec, CHU de Nantes.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|