Linked Life Data

8013523

Source:http://linkedlifedata.com/resource/pubmed/id/8013523

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-7-27
pubmed:abstractText
The effect of coronary insufficiency on the myocardial contraction pattern was studied in 11 thoracotomized cats using apical long axis echocardiograms and cross-oriented segments in the anterior midwall. Myocardial tissue blood flow was studied using radiolabelled microspheres. After circumflex coronary artery occlusion, ejection shortening increased on average 17% for circumferential segments (P < 0.05) and 61% for longitudinal segments (P < 0.001). Hyperkinesis was also validated as augmented anterior endocardial wall motion and wall thickening. Circumflex occlusion increased end-systolic sphericity of the left ventricle (P < 0.05). Subsequent underperfusion of the left coronary artery, in two discrete steps, decreased subendocardial blood flow by, on average, 36% (P < 0.001) and 75% (P < 0.001) vs the post-occlusion value, while subepicardial flow did not change. While subendocardial blood flow decreased by 36%, systolic shortening of the global major axis decreased, by, on average, 77% (P < 0.001), shortening of the longitudinal segments by 36% (P < 0.001), and systolic shortening of the minor axis by 18% (P < 0.05), whereas shortening of midwall circumferential segments did not change. This study shows that changes in myocardial contraction in both non-ischaemic and ischaemic regions during coronary insufficiency are most pronounced in the direction of the cardiac major axis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0195-668X
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
424-33
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Myocardial contraction patterns in non-ischaemic and ischaemic regions during acute coronary insufficiency.
pubmed:affiliation
Department of Surgery, University of Bergen, Haukeland Hospital, Norway.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't