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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-7-20
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pubmed:abstractText |
We report a case of malignant melanoma that appeared in a 56-year-old man with mycosis fungoides (stage Ia) during treatment with PUVA. The cumulative UVA dose was 1,177 J/cm2. The pigmented lesion was removed and PUVA therapy discontinued. Histological examination revealed a superficial spreading malignant melanoma (1.77 mm thick, Clark level IV). The delayed-type cutaneous hypersensitivity was studied. The presence of a second malignancy after mycosis fungoides and PUVA therapy may have been coincidental. Nevertheless, this case suggests that the immunosuppression induced by mycosis fungoides and by PUVA therapy might be a pathogenetic factor in the development of malignant melanoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:issn |
1018-8665
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
189
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
75-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8003794-Humans,
pubmed-meshheading:8003794-Male,
pubmed-meshheading:8003794-Melanoma,
pubmed-meshheading:8003794-Middle Aged,
pubmed-meshheading:8003794-Mycosis Fungoides,
pubmed-meshheading:8003794-Neoplasms, Second Primary,
pubmed-meshheading:8003794-PUVA Therapy,
pubmed-meshheading:8003794-Skin Neoplasms
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pubmed:year |
1994
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pubmed:articleTitle |
Cutaneous malignant melanoma appearing during photochemotherapy of mycosis fungoides.
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pubmed:affiliation |
Università degli Studi di Milano, Italia.
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pubmed:publicationType |
Journal Article,
Case Reports
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