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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1995-1-17
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pubmed:abstractText |
Conduction mediated by the slow inward (Ca2+) current occurs in vitro under specific experimental conditions but has not been documented in ventricular muscle in vivo during regional myocardial ischemia, perhaps because certain constituents of ischemia (including hypoxia and acidosis) may inhibit the Ca2+ current in this setting. We hypothesized that slow conduction mediated by the Ca2+ current could occur during acute ischemia in situations in which the extracellular K+ rise was more marked relative to the degree of acidosis, as may occur at ischemic boundaries.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0009-7322
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3009-17
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7994849-Animals,
pubmed-meshheading:7994849-Epinephrine,
pubmed-meshheading:7994849-Female,
pubmed-meshheading:7994849-Glyburide,
pubmed-meshheading:7994849-Heart,
pubmed-meshheading:7994849-Heart Conduction System,
pubmed-meshheading:7994849-Male,
pubmed-meshheading:7994849-Myocardial Ischemia,
pubmed-meshheading:7994849-Myocardium,
pubmed-meshheading:7994849-Potassium,
pubmed-meshheading:7994849-Swine,
pubmed-meshheading:7994849-Verapamil
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pubmed:year |
1994
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pubmed:articleTitle |
Marked activation delay caused by ischemia initiated after regional K+ elevation in in situ pig hearts.
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pubmed:affiliation |
Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill 27599-7075.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|