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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1994-12-1
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pubmed:abstractText |
Seventeen patients with a more than 5-month-history of angina pectoris were allocated a diet for 4 weeks. The diet was supplemented with 6.15 g of omega 3-polyunsaturated fatty acids (PUFA) in 125 g canned Far-Eastern sardine. This increased the proportion of eicosapentaenic (EPA) and docosahexaenic acids from 1.28 +/- 0.72 to 9.02 +/- 2.83% and from 2.48 +/- 0.91 to 6.54 +/- 2.01%, respectively; p = 0.0003) in the total serum lipid fraction. The levels of omega 6-PUFA decreased due to linoleic acid (from 24.9 +/- 3.9 to 19.7 +/- 5.2%, p = 0.0014). The EPA/arachidonic acid ratio rose from 0.23 +/- 0.11 to 1.76 +/- 0.58 (p < 0.001). The levels of triglycerides decreased by 36.4% (from 162.3 +/- 55.2 to 103.9 +/- 42.4 mg/dl; p < 0.0005); those of very low density lipoproteins and total cholesterol by 36 and 6.8%, respectively (from 32.5 +/- 11.0 to 20.8 +/- 8.5 mg/dl; p < 0.0005 and from 234.8 +/- 43.2 to 218.4 +/- 39.7 mg/dl; p < 0.05, respectively). The concentrations of high density lipoproteins remained unchanged. Thus, a short-term supplementation of canned Far-Eastern sardine to the diet of patients with CHD caused a substantial changes in blood fatty acid composition and favourable shifts in the levels of lipids and lipoproteins. This allows the Far-Eastern sardine to be regarded as a valuable source of omega 3-PUFA which can be used in the secondary prevention of coronary heart disease.
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pubmed:language |
rus
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Arachidonic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Docosahexaenoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Eicosapentaenoic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Omega-3,
http://linkedlifedata.com/resource/pubmed/chemical/Linoleic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Linoleic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, VLDL,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides
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pubmed:status |
MEDLINE
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pubmed:issn |
0022-9040
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7967323-Adult,
pubmed-meshheading:7967323-Aged,
pubmed-meshheading:7967323-Animals,
pubmed-meshheading:7967323-Arachidonic Acid,
pubmed-meshheading:7967323-Cholesterol,
pubmed-meshheading:7967323-Docosahexaenoic Acids,
pubmed-meshheading:7967323-Eicosapentaenoic Acid,
pubmed-meshheading:7967323-Fatty Acids, Omega-3,
pubmed-meshheading:7967323-Fishes,
pubmed-meshheading:7967323-Food, Fortified,
pubmed-meshheading:7967323-Food Preservation,
pubmed-meshheading:7967323-Humans,
pubmed-meshheading:7967323-Linoleic Acid,
pubmed-meshheading:7967323-Linoleic Acids,
pubmed-meshheading:7967323-Lipoproteins, HDL,
pubmed-meshheading:7967323-Lipoproteins, VLDL,
pubmed-meshheading:7967323-Male,
pubmed-meshheading:7967323-Middle Aged,
pubmed-meshheading:7967323-Myocardial Ischemia,
pubmed-meshheading:7967323-Time Factors,
pubmed-meshheading:7967323-Triglycerides
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pubmed:year |
1993
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pubmed:articleTitle |
[Dietary effect of omega-3 polyunsaturated fatty acid supplementation on blood fatty acids, lipid and lipoproteins in patients with ischemic heart disease].
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pubmed:publicationType |
Journal Article,
English Abstract
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