Linked Life Data

7947471

Source:http://linkedlifedata.com/resource/pubmed/id/7947471

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-12-28
pubmed:abstractText
A gel system is developed that undergoes a reversible volume phase transition in response to a small amount of urea. An N-isopropylacrylamide gel in which urease is immobilized by entrapping changes its equilibrium volume discontinuously when urea molecules are hydrolyzed by urease causing a change in pH that alters the osmotic balance of the gel triggering the phase transition. The system demonstrates a method of mechano-biochemical transformation where molecular recognition and biochemical reaction are achieved by an enzyme and the macroscopic amplification of the reaction is carried out by a gel capable of a volume phase transition. The work presented here is dedicated to Professor Allan S. Hoffman to honor his 60th birthday and his pioneering contribution to the science and technology of polymer gels, both as a scientist and as an educator.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0920-5063
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
35-40
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Biochemo-mechanical function of urease-loaded gels.
pubmed:affiliation
Department of Physics, Massachusetts Institute of Technology, Cambridge 02139.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't