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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1995-4-13
|
| pubmed:abstractText |
To further understand the relation between heterogeneously infarcted myocardium and fractionated electrograms, a computer model was used to test the hypothesis that the way electrogram metrics change with electrode location relates to statistical properties of the underlying myocardium. A sheet of Beeler-Reuter elements was coupled with cytoplasmic resistance to form cells. Junctional resistance values were assigned using a recursive randomization to produce a fractal pattern, simulating damage from disrupted blood supply. The pattern's correlation dimension, D, was a statistical measure of heterogeneity. Unipolar electrogram's amplitude, duration, number of inflections, peak frequency, bandwidth, and the rate of change of metrics with height were calculated. Analysis of variance indicated (P < .0001) that peak-to-peak amplitude and bandwidth decreased at a slower rate when height was increased above heterogeneous tissue as compared with homogeneous tissue. These findings could be useful during clinical mapping procedures as statistical estimates of tissue structure.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0022-0736
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
27 Suppl
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
171-8
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading | |
| pubmed:year |
1994
|
| pubmed:articleTitle |
Effects of coupling heterogeneity on fractionated electrograms in a model of nonuniformly anisotropic ventricular myocardium.
|
| pubmed:affiliation |
Bioengineering Graduate Group, University of California, San Francisco, CA 94143-1354.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|