Linked Life Data

7877989

Source:http://linkedlifedata.com/resource/pubmed/id/7877989

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:7877989rdf:typepubmed:Citationlld:pubmed
pubmed-article:7877989lifeskim:mentionsumls-concept:C0007634lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C0035820lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C0025914lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C0026809lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C0034821lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C0596901lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C0524637lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C0206190lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C0301704lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C0348035lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C1516044lld:lifeskim
pubmed-article:7877989lifeskim:mentionsumls-concept:C1883709lld:lifeskim
pubmed-article:7877989pubmed:issue5lld:pubmed
pubmed-article:7877989pubmed:dateCreated1995-4-4lld:pubmed
pubmed-article:7877989pubmed:abstractTextWe recently reported that oxidized low density lipoprotein (OxLDL), but not acetyl LDL (AcLDL), inhibited the binding and phagocytosis of nonopsonized, oxidatively damaged red blood cells (OxRBCs) by mouse peritoneal macrophages, implying the involvement of a "scavenger receptor" other than the AcLDL receptor. Numerous studies establish that loss of plasma membrane phospholipid asymmetry, which increases phosphatidylserine expression on the outer leaflet of the membrane, can play a key role in macrophage recognition of damaged and apoptotic cells. We report here that this recognition is in part attributable to the same mouse macrophage receptor that recognizes OxLDL. As described in an accompanying paper, this is a plasma membrane protein of 94-97 kDa. Phosphatidylserine liposomes show strong ligand binding to the same 94- to 97-kDa protein and this binding is inhibited by OxLDL but not by AcLDL. Inhibition of the RBC membrane phospholipid translocase by incubation with sodium vanadate caused a progressive increase in the appearance of phosphatidylserine on the cell surface and a parallel increase in the binding of these RBCs to macrophages, binding that was inhibited by OxLDL. Finally, OxLDL also inhibited the binding of sickled RBCs and apoptotic thymocytes to mouse macrophages. However, the latter was incomplete (approximately 50%), suggesting that other receptors are also involved. We suggest that the OxLDL receptor plays a significant role in recognition of damaged and apoptotic cells.lld:pubmed
pubmed-article:7877989pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:languageenglld:pubmed
pubmed-article:7877989pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:citationSubsetIMlld:pubmed
pubmed-article:7877989pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7877989pubmed:statusMEDLINElld:pubmed
pubmed-article:7877989pubmed:monthFeblld:pubmed
pubmed-article:7877989pubmed:issn0027-8424lld:pubmed
pubmed-article:7877989pubmed:authorpubmed-author:SteinbergDDlld:pubmed
pubmed-article:7877989pubmed:authorpubmed-author:SambranoG RGRlld:pubmed
pubmed-article:7877989pubmed:issnTypePrintlld:pubmed
pubmed-article:7877989pubmed:day28lld:pubmed
pubmed-article:7877989pubmed:volume92lld:pubmed
pubmed-article:7877989pubmed:ownerNLMlld:pubmed
pubmed-article:7877989pubmed:authorsCompleteYlld:pubmed
pubmed-article:7877989pubmed:pagination1396-400lld:pubmed
pubmed-article:7877989pubmed:dateRevised2009-11-18lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:meshHeadingpubmed-meshheading:7877989-...lld:pubmed
pubmed-article:7877989pubmed:year1995lld:pubmed
pubmed-article:7877989pubmed:articleTitleRecognition of oxidatively damaged and apoptotic cells by an oxidized low density lipoprotein receptor on mouse peritoneal macrophages: role of membrane phosphatidylserine.lld:pubmed
pubmed-article:7877989pubmed:affiliationDepartment of Medicine, University of California, San Diego, La Jolla 92093-0682.lld:pubmed
pubmed-article:7877989pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7877989pubmed:publicationTypeIn Vitrolld:pubmed
pubmed-article:7877989pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:7877989pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7877989lld:pubmed
More...