| pubmed-article:7836886 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7836886 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
| pubmed-article:7836886 | lifeskim:mentions | umls-concept:C0010092 | lld:lifeskim |
| pubmed-article:7836886 | lifeskim:mentions | umls-concept:C0085862 | lld:lifeskim |
| pubmed-article:7836886 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:7836886 | pubmed:dateCreated | 1995-3-1 | lld:pubmed |
| pubmed-article:7836886 | pubmed:abstractText | The rabbit corpus luteum possesses LH receptors that are coupled to adenylyl cyclase, but paradoxically it does not require LH as a luteotrophic factor for the maintenance of progesterone secretion. This suggests that rabbit luteal cells may not respond physiologically to LH. Therefore, the present study was undertaken to investigate the responsiveness of the rabbit corpus luteum of pseudopregnancy to human chorionic gonadotrophin (hCG) which acts on the same receptor as LH. Pseudopregnancy was induced by injection of 40 IU pregnant mare serum gonadotrophin followed 50 h later by an injection of 40 IU hCG (day 0). On days 7 and 11 of pseudopregnancy, corpora lutea were obtained and incubated for 2 or 5 h in the presence of either 0.1 or 1 microgram/ml hCG or 1 mM monobutyryl cyclic AMP (bcAMP). Neither hCG nor bcAMP stimulated progesterone production by the isolated corpus luteum, despite a sustained high rate of progesterone production by the tissue throughout the incubation period. By contrast, Graafian follicles removed from the same ovaries and incubated under the same conditions responded both to hCG and bcAMP with large increases in progesterone production. To determine whether the cyclic AMP content of the corpus luteum was altered by in vitro exposure to hCG, day 7 and day 11 corpora lutea were incubated for 5 or 15 min with various concentrations of hCG, and cyclic AMP in the tissue was then measured. Even at the highest concentration of hCG tested (10 micrograms/ml), the cyclic AMP content of the corpus luteum was unaltered.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:7836886 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7836886 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7836886 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7836886 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7836886 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7836886 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7836886 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7836886 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7836886 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7836886 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7836886 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7836886 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7836886 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:7836886 | pubmed:issn | 0022-0795 | lld:pubmed |
| pubmed-article:7836886 | pubmed:author | pubmed-author:KostyoJ LJL | lld:pubmed |
| pubmed-article:7836886 | pubmed:author | pubmed-author:KeyesP LPL | lld:pubmed |
| pubmed-article:7836886 | pubmed:author | pubmed-author:TownsRR | lld:pubmed |
| pubmed-article:7836886 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7836886 | pubmed:volume | 143 | lld:pubmed |
| pubmed-article:7836886 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7836886 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7836886 | pubmed:pagination | 423-31 | lld:pubmed |
| pubmed-article:7836886 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
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| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:meshHeading | pubmed-meshheading:7836886-... | lld:pubmed |
| pubmed-article:7836886 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7836886 | pubmed:articleTitle | The autonomy of the rabbit corpus luteum. | lld:pubmed |
| pubmed-article:7836886 | pubmed:affiliation | Department of Physiology, University of Michigan Medical School, Ann Arbor 48109. | lld:pubmed |
| pubmed-article:7836886 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7836886 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
