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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1995-2-27
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pubmed:abstractText |
The polymerase chain reaction was used to detect hepatitis C virus infection in patients who had previously been reported to have developed non-A, non-B hepatitis after intravenous immunoglobulin infusion. Of the 33 patients with intravenous immunoglobulin associated non-A, non-B hepatitis studied, HCV RNA could be detected in 15 out of 17 patients (88%) who were HCV RNA negative prior to the development of non-A, non-B hepatitis after implicated intravenous immunoglobulin batches. Similarly, eight out of nine patients (89%) in whom no sample was available for polymerase chain reaction testing prior to intravenous immunoglobulin therapy, had detectable HCV RNA after intravenous immunoglobulin therapy with intravenous immunoglobulin batches implicated in non-A, non-B hepatitis transmission. Two of the three intravenous immunoglobulin preparations implicated in non-A, non-B hepatitis transmissions that were available for polymerase chain reaction testing also had detectable HCV RNA, confirming that hepatitis C virus is the implicated virus in intravenous immunoglobulin-associated non-A, non-B hepatitis.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0168-8278
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
21
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
455-60
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7836718-Hepacivirus,
pubmed-meshheading:7836718-Hepatitis C,
pubmed-meshheading:7836718-Humans,
pubmed-meshheading:7836718-Immunoglobulins, Intravenous,
pubmed-meshheading:7836718-Immunologic Deficiency Syndromes,
pubmed-meshheading:7836718-Incidence,
pubmed-meshheading:7836718-Polymerase Chain Reaction,
pubmed-meshheading:7836718-RNA, Viral,
pubmed-meshheading:7836718-Retrospective Studies
|
pubmed:year |
1994
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pubmed:articleTitle |
Hepatitis C virus transmission by intravenous immunoglobulin.
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pubmed:affiliation |
Edinburgh & South East Scotland Blood Transfusion Service, UK.
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pubmed:publicationType |
Journal Article
|