| pubmed-article:7762523 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7762523 | lifeskim:mentions | umls-concept:C0012171 | lld:lifeskim |
| pubmed-article:7762523 | lifeskim:mentions | umls-concept:C0003595 | lld:lifeskim |
| pubmed-article:7762523 | lifeskim:mentions | umls-concept:C0597298 | lld:lifeskim |
| pubmed-article:7762523 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:7762523 | lifeskim:mentions | umls-concept:C0445604 | lld:lifeskim |
| pubmed-article:7762523 | lifeskim:mentions | umls-concept:C0449774 | lld:lifeskim |
| pubmed-article:7762523 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:7762523 | pubmed:dateCreated | 1995-6-29 | lld:pubmed |
| pubmed-article:7762523 | pubmed:abstractText | We examined the effects of replacing dietary fat with carbohydrates on high-density-lipoprotein (HDL) subclasses as measured by nondenaturing polyacrylamide-gradient-gel electrophoresis. One hundred five men received a 6-wk low-fat diet (24% of total energy) and a 6-wk high-fat diet (46% of energy) in a crossover design. Absorbency of protein stain was measured within five HDL subclasses: HDL3c (7.2-7.8 nm), HDL3b (7.8-8.2 nm), HDL3a (8.2-8.8 nm), HDL2a (8.8-9.7 nm), and HDL2b (9.7-12 nm). The low-density-lipoprotein-(LDL) subclass pattern was determined by gradient-gel electrophoresis, with pattern B men defined as having an LDL-predominant peak diameter < or = 25.5 nm and an LDL distribution skewed toward larger size particles. On the high-fat diet, 18 men exhibited LDL-subclass pattern B and 87 men exhibited the alternative LDL pattern A. Twelve men had the apolipoprotein (apo) epsilon 2 allele. Replacing dietary fat with carbohydrates 1) significantly decreased HDL3a, HDL2a, and HDL2b; 2) reduced HDL2b significantly more in pattern A than in pattern B men; and 3) increased plasma HDL3b concentrations significantly more in those men with the epsilon 2 allele. Our results suggest that unfavorable HDL changes were significantly more likely to occur in men who had LDL-subclass pattern A or the apo epsilon allele than in men who had pattern B or lacked the epsilon 2 allele. | lld:pubmed |
| pubmed-article:7762523 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7762523 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7762523 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7762523 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7762523 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:7762523 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7762523 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7762523 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7762523 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7762523 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7762523 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7762523 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7762523 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:7762523 | pubmed:issn | 0002-9165 | lld:pubmed |
| pubmed-article:7762523 | pubmed:author | pubmed-author:KraussR MRM | lld:pubmed |
| pubmed-article:7762523 | pubmed:author | pubmed-author:WilliamsP TPT | lld:pubmed |
| pubmed-article:7762523 | pubmed:author | pubmed-author:DreonD MDM | lld:pubmed |
| pubmed-article:7762523 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7762523 | pubmed:volume | 61 | lld:pubmed |
| pubmed-article:7762523 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7762523 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7762523 | pubmed:pagination | 1234-40 | lld:pubmed |
| pubmed-article:7762523 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:meshHeading | pubmed-meshheading:7762523-... | lld:pubmed |
| pubmed-article:7762523 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7762523 | pubmed:articleTitle | Effects of dietary fat on high-density-lipoprotein subclasses are influenced by both apolipoprotein E isoforms and low-density-lipoprotein subclass patterns. | lld:pubmed |
| pubmed-article:7762523 | pubmed:affiliation | Life Sciences Division, Lawrence Berkeley Laboratory, Berkeley, CA 94720, USA. | lld:pubmed |
| pubmed-article:7762523 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7762523 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:7762523 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7762523 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:7762523 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:7762523 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
