Linked Life Data

7732977

Source:http://linkedlifedata.com/resource/pubmed/id/7732977

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1995-5-31
pubmed:abstractText
The objective of this study was to assess the use of coronary stenosis velocity in the determination of translesional pressure gradients. In the physiologic assessment of coronary stenosis, the accelerated intracoronary flow velocity within a narrowing has correlated with minimal lesion cross-sectional area according to the continuity equation. In large conduits the jet velocity can determine pressure gradients when used in the Bernouilli equation. However, the use of intralesional flow velocity for calculation of translesional pressure gradients by the simplified Bernouilli equation (delta P = 4V2) may be inaccurate in small (< 5 mm diameter) conduits. Translesional pressure (2.2F catheter) and flow velocity (0.018-inch guidewire) were measured in a single coronary artery in 23 patients undergoing diagnostic angiography or angioplasty. The electronically determined mean of phasic proximal and distal pressure and planimetry of the instantaneous phasic pressure gradient were used and compared with the instantaneous velocity calculations of pressure by the simplified Bernouilli formula with both maximal jet velocity and a modified formula including proximal velocity. The mean measured translesional pressure gradient was 18 +/- 13 mm Hg (range 0 to 50 mm Hg) and was equivalent to the instantaneous average pressure gradient by planimetry. The maximal jet velocity was 125 +/- 40 cm/sec (range 63 to 250 cm/sec), yielding a calculated pressure gradient of 3 +/- 3 mm Hg. The calculated pressure gradient by the simplified Bernouilli equation correlated poorly with the measured translesional gradient (r = 0.27, F = 1.63, p = 0.21).(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0002-8703
pubmed:author
pubmed:issnType
Print
pubmed:volume
129
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
887-94
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Hemodynamic significance of coronary jet velocity in patients: limitations of the Bernouilli equation in small conduits.
pubmed:affiliation
Department of Internal Medicine, St. Louis University Health Sciences Center, MO, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't