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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1995-5-18
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pubmed:abstractText |
The planum temporale of the temporal cortex was investigated post-mortem in 24 schizophrenic patients and 24 age- and sex-matched control subjects. Schizophrenic patients demonstrated a 20% volume reduction of the left planum temporale (p = 0.032), whereas on the right side, there was a trend for increase in male schizophrenics (+22%, p = 0.17), while in female patients the volume was moderately decreased (-6%, p = 0.74). The mean anterior-posterior diameter of the planum temporale was significantly reduced in the left hemisphere (-20%, p = 0.008), but unchanged on the right side. The asymmetry coefficients (Galaburda et al. (1987) Neuropsychologia 25, 853-868) for the planum temporale cortex volume (p = 0.02) and anterior-posterior diameter (p = 0.002) but not for mean area (p = 0.61) were significantly different between schizophrenics and control subjects. These data support the idea of disturbed cerebral laterality in schizophrenia. The implications of methodology and patient samples are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0920-9964
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-76
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pubmed:dateRevised |
2010-9-2
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pubmed:meshHeading |
pubmed-meshheading:7710997-Adult,
pubmed-meshheading:7710997-Aged,
pubmed-meshheading:7710997-Brain Mapping,
pubmed-meshheading:7710997-Cephalometry,
pubmed-meshheading:7710997-Dominance, Cerebral,
pubmed-meshheading:7710997-Female,
pubmed-meshheading:7710997-Humans,
pubmed-meshheading:7710997-Male,
pubmed-meshheading:7710997-Middle Aged,
pubmed-meshheading:7710997-Psychiatric Status Rating Scales,
pubmed-meshheading:7710997-Reference Values,
pubmed-meshheading:7710997-Schizophrenia,
pubmed-meshheading:7710997-Schizophrenic Psychology,
pubmed-meshheading:7710997-Sex Factors,
pubmed-meshheading:7710997-Temporal Lobe
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pubmed:year |
1995
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pubmed:articleTitle |
Disturbed planum temporale asymmetry in schizophrenia. A quantitative post-mortem study.
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pubmed:affiliation |
Department of Psychiatry, University of Düsseldorf, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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