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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-5-9
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pubmed:abstractText |
The temporal expression pattern of jun genes was studied in the hippocampal slice preparation. Slices were kept either in a physiological Ringer solution or a modified medium, substituting calcium (Ca2+) by magnesium (Mg2+). All three jun genes were expressed in a circumscribed, independent fashion with respect to distribution, intensity and time course. c-jun and junD were expressed strongly throughout the hippocampus with a shift from DG to CA1 to CA3. junB expression was confined to DG and CA1, but substitution of Ca2+ by Mg2+ led to profound changes: the signal rose earlier, was prolonged, strongly enhanced and more widespread. Our findings suggest, that changes in differential expression of jun gene transcripts are important for parallel processing of non-convergent stimuli.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Isotonic Solutions,
http://linkedlifedata.com/resource/pubmed/chemical/Magnesium,
http://linkedlifedata.com/resource/pubmed/chemical/Molecular Probes,
http://linkedlifedata.com/resource/pubmed/chemical/Ringer's solution
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0959-4965
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
101-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7703394-Animals,
pubmed-meshheading:7703394-Base Sequence,
pubmed-meshheading:7703394-Calcium,
pubmed-meshheading:7703394-Gene Expression Regulation,
pubmed-meshheading:7703394-Genes, jun,
pubmed-meshheading:7703394-Hippocampus,
pubmed-meshheading:7703394-Isotonic Solutions,
pubmed-meshheading:7703394-Magnesium,
pubmed-meshheading:7703394-Molecular Probes,
pubmed-meshheading:7703394-Molecular Sequence Data,
pubmed-meshheading:7703394-Perfusion,
pubmed-meshheading:7703394-Rats,
pubmed-meshheading:7703394-Rats, Wistar
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pubmed:year |
1994
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pubmed:articleTitle |
Differential expression of c-jun, junB and junD in rat hippocampal slices.
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pubmed:affiliation |
Department of Neurobiology, Max-Planck-Institute of Biophysical Chemistry, Göttingen, Germany.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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