Linked Life Data

7668170

Source:http://linkedlifedata.com/resource/pubmed/id/7668170

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-10-10
pubmed:abstractText
The purpose of this study was to evaluate the histologic changes that occur after dermabrasion and chemical peel in an animal model that has been pretreated with topical Retin-A. Since human skin and guinea pig skin are very similar in architecture, pretreatment of the latter with Retin-A may reflect what would occur in human skin. Twelve nude Hartley white guinea pigs were used in our study. Six were pretreated with topical Retin-A and six were controls. Each guinea pig underwent chemical peel and dermabrasion. The wounded areas were watched for clinical progression of healing and biopsied. Both clinical observation and histology revealed that those animals pretreated with Retin-A healed much quicker than the control animals. This was found to be statistically significant with p = 0.05. This study implies that if patients are treated with Retin-A before undergoing chemical peel or dermabrasion, they will likely observe accelerated healing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0364-216X
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-6
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:articleTitle
Histologic study of dermabrasion and chemical peel in an animal model after pretreatment with Retin-A.
pubmed:publicationType
Journal Article