|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003250,
umls-concept:C0005854,
umls-concept:C0006104,
umls-concept:C0006901,
umls-concept:C0033147,
umls-concept:C0086418,
umls-concept:C0439831,
umls-concept:C0597601,
umls-concept:C1167622,
umls-concept:C1448132,
umls-concept:C1510827,
umls-concept:C1515655,
umls-concept:C1533691
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1995-10-6
|
|
pubmed:abstractText |
The ability of monoclonal antibodies against the human insulin receptor to undergo transcytosis through the blood-brain barrier (BBB) was examined in the present studies.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0724-8741
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
12
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
807-16
|
|
pubmed:dateRevised |
2010-3-24
|
|
pubmed:meshHeading |
pubmed-meshheading:7667183-Animals,
pubmed-meshheading:7667183-Antibodies, Monoclonal,
pubmed-meshheading:7667183-Antibody Affinity,
pubmed-meshheading:7667183-Blood-Brain Barrier,
pubmed-meshheading:7667183-Brain,
pubmed-meshheading:7667183-Capillaries,
pubmed-meshheading:7667183-Drug Delivery Systems,
pubmed-meshheading:7667183-Endocytosis,
pubmed-meshheading:7667183-Female,
pubmed-meshheading:7667183-Humans,
pubmed-meshheading:7667183-Immunohistochemistry,
pubmed-meshheading:7667183-Macaca mulatta,
pubmed-meshheading:7667183-Male,
pubmed-meshheading:7667183-Mathematics,
pubmed-meshheading:7667183-Mice,
pubmed-meshheading:7667183-Radioligand Assay,
pubmed-meshheading:7667183-Receptor, Insulin
|
|
pubmed:year |
1995
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|
pubmed:articleTitle |
Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate.
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|
pubmed:affiliation |
Department of Medicine and Brain Research Institute, UCLA School of Medicine 90024, USA.
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|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
|
