Linked Life Data

7662882

Source:http://linkedlifedata.com/resource/pubmed/id/7662882

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1995-10-10
pubmed:abstractText
The stress-induced HSP72 expression in bovine oligodendrocytes (OL) in culture was investigated following exposure to heat stress, oxidative stress and cytokines by immunoblotting and immunocytochemistry. Under the unstressed condition, HSP72 was expressed in a small number (3%) of OL. After exposure to heat stress, the level of HSP72 expression in OL was elevated significantly and an intense HSP72 immunolabelling was identified in almost all OL, while HSP72 was not induced by exposure to hydrogen peroxide (10 microM) or glucose oxidase (20 mU ml-1). The level of HSP72 expression was not elevated by treatment with interleuken (IL)-1 alpha (10 ng ml-1), IL-1 beta (10 ng ml-1), tumour necrosis factor (TNF)-alpha (200 ng ml-1), or TNF-beta (200 ng ml-1). Our results indicate that HSP72 is upregulated in cultured bovine OL by heat stress but not by oxidative stress or cytokines such as IL-1 and TNF.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0959-4965
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1081-4
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Constitutive and inducible expression of heat shock protein HSP72 in oligodendrocytes in culture.
pubmed:affiliation
Department of Medicine, University of British Columbia, Vancouver, Canada.
pubmed:publicationType
Journal Article