Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-10-4
pubmed:abstractText
The causes of the wide spectrum of severity in malaria have only partly been elucidated. There are theoretical reasons for thinking that the infecting dose may influence the severity, but evidence is scare. We have analysed the records of 82 non-immune neurosyphilis patients bitten by a known number of mosquitoes infected with one of 3 strains of Plasmodium falciparum, whose treatment was delayed. After controlling for strain, the number of mosquitoes was not associated with the prepatent period nor with any of the outcome measures. For one of the main strains, patients with shorter prepatent periods were more likely to receive treatment during the acute phase of the infection, but no other association with measures of severity was found. This study suggest that infecting dose is unlikely to be an important determinant of severity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0035-9203
pubmed:author
pubmed:issnType
Print
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
281-3
pubmed:dateRevised
2009-9-29
pubmed:meshHeading
pubmed:articleTitle
Infecting dose and severity of falciparum malaria.
pubmed:affiliation
Department of Epidemiology and Population Sciences, London School of Hygiene and Tropical Medicine, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't