Linked Life Data

7642311

Source:http://linkedlifedata.com/resource/pubmed/id/7642311

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pubmed-article:7642311pubmed:abstractTextThe course of infection with Eimeria vermiformis in C57BL/6J; NK cell-defective C57BL/6J bg/bg; BALB/c; T-cell-defective BALB/c nu/nu; and T-cell-, B-cell-, and NK cell-defective BALB/c x C57BL/6 scid/scid bg/bg mice was monitored. For young C57BL/6J mice, the bg/bg mutants consistently produced fewer oocysts than the controls; there were no differences between older mice of these strains. Wild-type BALB/c mice were more resistant to infection than the nu/nu and scid/scid bg/bg mutants, but there was no difference between the mutants. Treatment of BALB/c mice with poly(I.C) had no effect on the course of infection. These findings confirm the ineffectiveness of NK cells in this system.lld:pubmed
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pubmed-article:7642311pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:7642311pubmed:articleTitleCytotoxic effects of natural killer cells have no significant role in controlling infection with the intracellular protozoon Eimeria vermiformis.lld:pubmed
pubmed-article:7642311pubmed:affiliationDepartment of Immunology and Pathology, Institute for Animal Health, Compton, Nr. Newbury, Berkshire, United Kingdom.lld:pubmed
pubmed-article:7642311pubmed:publicationTypeJournal Articlelld:pubmed
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