pubmed-article:7608589 | pubmed:abstractText | In mongrel dogs undergoing left anterior sleeve lobectomy, the role of bronchial circulation at the site of bronchial anastomosis was studied. Mucosal hemoglobin concentration and oxygen saturation were measured by spectral analysis of light reflected from the mucosal surface. The main bronchus was not resected in ten dogs (Group A). In ten other dogs (Group B), the main residual bronchus consisted of one or two rings. The following results were obtained. 1) The length of the main residual bronchus influenced the recovery of bronchial circulation following sleeve lobectomy. In Group B, arterial blood supply to the distal bronchial wall was better. Wound healing showed rapid progress from day 5, as was evident from the finding that bronchial arteries distal to the anastomosis were filled with proximal and mediastenal arterial blood. 2) Mucosal changes in bronchial anastomosis were the same for Groups A and B, as indicated by endoscopic examinations. In Group B, active neovascular proliferation was detected at the distal anastomotic site by microscopic examination. 3) In both groups, the micro-abscee could be seen at the anastomotic site at day 21. Bronchial anastomosis following sleeve lobectomy would thus appear to be complete on day 21 or thereafter. | lld:pubmed |