Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-8-14
pubmed:databankReference
pubmed:abstractText
We report the cloning of a cDNA encoding GliPR (glioma pathogenesis-related protein), a protein that is structurally similar to plant pathogenesis-related proteins. The GLIPR gene is highly expressed in the human brain tumor, glioblastoma multiforme/astrocytoma, but neither in normal fetal or adult brain tissue, nor in other nervous system tumors. GliPR shares up to 50% amino acid (aa) homology with plant pathogenesis-related proteins, group 1, over a region that comprises almost two thirds of the protein. We speculate that there may be functional similarities between the human and plant proteins as well.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0378-1119
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
159
pubmed:geneSymbol
GLIPR
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
131-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:7607567-Amino Acid Sequence, pubmed-meshheading:7607567-Astrocytoma, pubmed-meshheading:7607567-Base Sequence, pubmed-meshheading:7607567-Brain Neoplasms, pubmed-meshheading:7607567-Cloning, Molecular, pubmed-meshheading:7607567-DNA, Complementary, pubmed-meshheading:7607567-Gene Expression Regulation, Neoplastic, pubmed-meshheading:7607567-Glioblastoma, pubmed-meshheading:7607567-Humans, pubmed-meshheading:7607567-Molecular Sequence Data, pubmed-meshheading:7607567-Neoplasm Proteins, pubmed-meshheading:7607567-Nerve Tissue Proteins, pubmed-meshheading:7607567-Plant Proteins, pubmed-meshheading:7607567-RNA, Messenger, pubmed-meshheading:7607567-RNA, Neoplasm, pubmed-meshheading:7607567-Sequence Alignment, pubmed-meshheading:7607567-Sequence Analysis, DNA, pubmed-meshheading:7607567-Sequence Homology, Amino Acid, pubmed-meshheading:7607567-Tumor Cells, Cultured
pubmed:year
1995
pubmed:articleTitle
The human glioma pathogenesis-related protein is structurally related to plant pathogenesis-related proteins and its gene is expressed specifically in brain tumors.
pubmed:affiliation
Department of Neurologic Surgery, University of California, San Francisco 94143, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't