| pubmed-article:7600290 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C0026764 | lld:lifeskim |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C0020205 | lld:lifeskim |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C1442823 | lld:lifeskim |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C0017350 | lld:lifeskim |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C0598496 | lld:lifeskim |
| pubmed-article:7600290 | lifeskim:mentions | umls-concept:C1292733 | lld:lifeskim |
| pubmed-article:7600290 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:7600290 | pubmed:dateCreated | 1995-8-10 | lld:pubmed |
| pubmed-article:7600290 | pubmed:abstractText | Recent experiments involving disruption of the Oct-2 gene have shown that this largely B cell-restricted transcription factor is not required in the early stages of B cell development. However, B cells that lack Oct-2 may be blocked from differentiation past the surface immunoglobulin-positive stage. To identify a possible function for Oct-2 in the late stage immunoglobulin-secreting cell, we have used the method of somatic cell fusion. When the immunoglobulin-producing myeloma MPC11 is fused to a T lymphoma, Oct-2 production ceases, as does the expression of immunoglobulin, J chain, and several other B cell-specific gene products. In the present study, we show that by preventing the loss of Oct-2 in the hybrid cells, we can preserve expression of all other tested B cell-specific genes. These results establish a central role for Oct-2 in maintaining the genetic program of the immunoglobulin-secreting plasmacyte. | lld:pubmed |
| pubmed-article:7600290 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7600290 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7600290 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7600290 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:7600290 | pubmed:issn | 1074-7613 | lld:pubmed |
| pubmed-article:7600290 | pubmed:author | pubmed-author:KadeschTT | lld:pubmed |
| pubmed-article:7600290 | pubmed:author | pubmed-author:EckhardtL ALA | lld:pubmed |
| pubmed-article:7600290 | pubmed:author | pubmed-author:RoseV LVL | lld:pubmed |
| pubmed-article:7600290 | pubmed:author | pubmed-author:RadomskaH SHS | lld:pubmed |
| pubmed-article:7600290 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7600290 | pubmed:volume | 1 | lld:pubmed |
| pubmed-article:7600290 | pubmed:geneSymbol | Oct-2 | lld:pubmed |
| pubmed-article:7600290 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7600290 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7600290 | pubmed:pagination | 623-34 | lld:pubmed |
| pubmed-article:7600290 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:meshHeading | pubmed-meshheading:7600290-... | lld:pubmed |
| pubmed-article:7600290 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7600290 | pubmed:articleTitle | Constitutively expressed Oct-2 prevents immunoglobulin gene silencing in myeloma x T cell hybrids. | lld:pubmed |
| pubmed-article:7600290 | pubmed:affiliation | Department of Biological Sciences, Hunter College, City University of New York, New York 10021, USA. | lld:pubmed |
| pubmed-article:7600290 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7600290 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7600290 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:18987 | entrezgene:pubmed | pubmed-article:7600290 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7600290 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7600290 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7600290 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7600290 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7600290 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7600290 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7600290 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7600290 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7600290 | lld:pubmed |
