Linked Life Data

7448399

Source:http://linkedlifedata.com/resource/pubmed/id/7448399

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1981-3-24
pubmed:abstractText
A study was made of a change in the cell composition of the liver during regeneration induced by repeated (up to 8 times) administration of carbon tetrachloride with a one-month interval. The second administration entailed total polyploidization of hepatocytes. The subsequent stimulation of the regeneration process greatly enhanced polyploidization, with octoploid hepatocytes becoming the predominant cell type. The upper limit of polyploidization reached 64 n. The maximum mean ploidy amounted on the average to 11.1 n. for the nucleus and 12.5 n for the cell. These values were 2.8 and 2.2 higher, respectively, than the initial ploidy level. Proliferative potencies of polyploid hepatocytes and the mechanisms of retention of an exceedingly small number of diploid cells during intensive reparative liver growth are discussed.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0365-9615
pubmed:author
pubmed:issnType
Print
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
614-6
pubmed:dateRevised
2008-10-8
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
[Polyploidization of mouse hepatocytes following repeated exposure to carbon tetrachloride].
pubmed:publicationType
Journal Article, English Abstract