Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1980-10-27
pubmed:abstractText
The mechanism of aspirin analgesia is still unclear, but it is generally assumed that aspirin exerts its analgesic effect mainly on peripheral nociceptors. In this study, we demonstrate possible brain effects of 975 mg aspirin in man. When brain electrical potentials evoked by painful electrical tooth shocks were examined, aspirin was observed to significantly reduce the amplitude of the late waveform components, but it did not affect the earlier components. Since our earlier findings suggest that early waveform components reflect the energy transmission and the late components manifest the brain activities in an individual's perception of painful information, we postulate that aspirin may act centrally in pain processing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-4819
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
359-64
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Aspirin analgesia evaluated by event-related potentials in man: possible central action in brain.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.