|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005052,
umls-concept:C0006644,
umls-concept:C0034715,
umls-concept:C0037633,
umls-concept:C0185125,
umls-concept:C0205531,
umls-concept:C0226896,
umls-concept:C0442027,
umls-concept:C0599956,
umls-concept:C0871261,
umls-concept:C1261322,
umls-concept:C1382100,
umls-concept:C1527415,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1982-6-24
|
|
pubmed:abstractText |
In a lifetime experiment benzo(a)pyrene (B(a)P) was administered to Sprague-Dawley rats either as an admixture to the diet or by gavage in an aqueous 1.5% caffeine solution. Dissolved benzo(a)pyrene induced more tumors of the forestomach than undissolved benzo(a)pyrene. The 1.5% caffeine solution (annual dose 27 g/kg) did not exert any carcinogenic activity under the conditions of this bioassay.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0171-5216
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
102
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
153-7
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:7338532-Administration, Oral,
pubmed-meshheading:7338532-Animals,
pubmed-meshheading:7338532-Benzopyrenes,
pubmed-meshheading:7338532-Caffeine,
pubmed-meshheading:7338532-Drug Synergism,
pubmed-meshheading:7338532-Female,
pubmed-meshheading:7338532-Male,
pubmed-meshheading:7338532-Neoplasms, Experimental,
pubmed-meshheading:7338532-Rats,
pubmed-meshheading:7338532-Rats, Inbred Strains,
pubmed-meshheading:7338532-Solubility,
pubmed-meshheading:7338532-Solutions
|
|
pubmed:year |
1981
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|
pubmed:articleTitle |
Investigation of the tumorigenic response to benzo(a)pyrene in aqueous caffeine solution applied orally to Sprague-Dawley rats.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
