Linked Life Data

7228764

Source:http://linkedlifedata.com/resource/pubmed/id/7228764

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1981-7-9
pubmed:abstractText
Pressure-volume (PV) curves and single-breath nitrogen (SBN) washout traces were obtained in 32 excised human lungs. Comparison of the volumes at the onset of phage IV of the SBN traces (V phase IV) and the volumes at the inflection points (VIP) of the PV curves revealed V phase IV to be significantly larger than VIP. We postulated that V phase IV was caused by bulk airway closure and that the difference between V phase IV and VIP was due to collateral ventilation. To test this we correlated V phas IV -- VIP with age and emphysema grades of the lungs. Significant correlations were obtained, demonstrating that with increasing age and emphysema grade V phase IV -- VIP also increased. This is consistent with the documented evidence for decreased resistance to collateral ventilation with increasing age and emphysema. In addition, in a total of 86 lungs we demonstrated that with increasing age and emphysema there is an increasing incidence of total lack of sigmoid deviation in the PV curve.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0161-7567
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
927-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Collateral ventilation in excised human lungs.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't