Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-6-13
pubmed:abstractText
The effect of combined cold and pharmacological ischaemic cardioplegia on the structural integrity and the degree of the functional activity of the inbuilt intrinsic sympatho-adrenergic nervous system was studied by means of fluorescence microscopy of atrial myocardial biopsies obtained in the course of coronary bypass surgery on 8 consecutive patients. The specimens were taken 1) before starting extracorporeal circulation (controls), and 2) at decannulation (i.e. after cold cardioplegic ischaemic asystole and subsequent coronary reperfusion). The cardioplegia was induced by perfusing the coronary arteries via the aortic root with cold "cardioplegic solution" after starting extracorporeal circulation, venting the left ventricle and cross-clamping the ascending aorta. The specimens were processed for semi-quantitative fluorescence histochemical analysis. No changes were observed. Thus, it is concluded that the procedure of the combined cold and pharmacological ischaemic cardioplegia obviously preserves well the neural noradrenalin of the heart, a vital means of compensating for decreasing myocardial contractility. As the clinical parallelism, all patients made a smooth convalescence.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0036-5580
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
267-73
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Effect of combined cold and pharmacological ischaemic cardioplegia on myocardial intrinsic sympatho-adrenergic system during coronary bypass surgery.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't