Linked Life Data

7009817

Source:http://linkedlifedata.com/resource/pubmed/id/7009817

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-5-13
pubmed:abstractText
The effect of pneumococcal vaccination on antibodies to Streptococcus pneumoniae type 14, group B streptococcus type III, and AB blood group antigens was studied in 40 vaccinated adults. Fourfold or greater increases in type-specific IgG antibody to Pn-14 were found in 26 of 40 vaccines (mean increase 6.4-fold) and against GBS-III in 16 of the 40 (mean increase 2.9-fold) by an indirect immunofluorescence assay. However, only six of the 26 vaccinees with low levels (titers less than or equal to 20) of GBS-III antibody in prevaccination sera developed titers greater than 20 after vaccination. Thus, vaccination with polyvalent pneumococcal vaccine does not reliably induce high levels of IF antibody to GBS-III. Fourfold or greater increases in IgG isohemagglutinins against blood group A cells were also found in 22 of 27 vaccines (mean increase 4.5-fold) and against blood group B cells in nine of 34 (mean increase 1.7-fold) using the indirect anti-human globulin test. Chromatographic fractionation of selected sera confirmed that the anti-A isohemagglutinins stimulated in group O subjects were of the IgG class. Thus, pneumococcal vaccination during incompatible pregnancy could potentiate AO hemolytic disease of the newborn infant.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-3476
pubmed:author
pubmed:issnType
Print
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
374-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Antibody response to group B streptococcus type III and AB blood group antigens induced by pneumococcal vaccine.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.