Linked Life Data

6887161

Source:http://linkedlifedata.com/resource/pubmed/id/6887161

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-10-8
pubmed:abstractText
Enzyme-linked immunosorbent assays (ELISA) were used to measure IgG, IgM and IgM rheumatoid factor (IgM RF) production in supernatants of pokeweed mitogen (PWM) stimulated peripheral blood mononuclear cells (PBMNC) of patients with rheumatoid arthritis (RA) and controls. Spontaneous and stimulated IgG and IgM production by RA and controls was comparable, but spontaneous production of IgM RF was only observed in RA and was related to their drug therapy. A significant difference was found between PWM induced IgM RF production in RA and controls and also between patients on "second-line" and on nonsteroidal anti-inflammatory drugs (NSAID). In addition, spontaneous IgM RF production by synovial fluid cells was significantly higher than the paired PBMNC.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
364-72
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Spontaneous and pokeweed mitogen induced in vitro immunoglobulin and IgM rheumatoid factor production by peripheral blood and synovial fluid mononuclear cells in rheumatoid arthritis.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't