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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1983-10-28
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pubmed:abstractText |
The chromosomes of unstimulated and stimulated blood lymphocytes from 5 cases with B-cell prolymphocytic leukemia (PLL) were examined following the use of polyclonal B-cell activators (PBA). Banding techniques revealed a common and specific chromosome abnormality to be present in each of the cases, which was due to a translocation between chromosomes 6 and 12 (t(6;12)(q15;p13]. The fact that this specific chromosome change has not been reported in other lymphoproliferative disorders may indicate that PLL is a distinct clinical entity and different from other lymphoproliferative disorders, whether it occurs de novo or complicates chronic lymphocytic leukemia (CLL).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0006-4971
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
729-36
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6882921-Aged,
pubmed-meshheading:6882921-Chromosome Aberrations,
pubmed-meshheading:6882921-Chromosomes, Human, 1-3,
pubmed-meshheading:6882921-Chromosomes, Human, 16-18,
pubmed-meshheading:6882921-Chromosomes, Human, 19-20,
pubmed-meshheading:6882921-Chromosomes, Human, 21-22 and Y,
pubmed-meshheading:6882921-Chromosomes, Human, 6-12 and X,
pubmed-meshheading:6882921-Female,
pubmed-meshheading:6882921-Humans,
pubmed-meshheading:6882921-Karyotyping,
pubmed-meshheading:6882921-Leukemia, Lymphoid,
pubmed-meshheading:6882921-Male,
pubmed-meshheading:6882921-Sex Chromosomes
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pubmed:year |
1983
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pubmed:articleTitle |
Possible specific chromosome change in prolymphocytic leukemia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
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