Linked Life Data

6861282

Source:http://linkedlifedata.com/resource/pubmed/id/6861282

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1983-8-11
pubmed:abstractText
We isolated mutants of the nematode Caenorhabditis elegans resistant to 12-O-tetradecanoylphorbol-13-acetate (TPA). The TPA-resistant mutants, although they grew somewhat smaller than normal, reproduced well and behaved normally in TPA; they also did similarly in another phorbol ester tumor promoter, phorbol-12,13-didecanoate (PDD), thus proving they are also resistant to PDD. All the mutations defined by these TPA-resistant mutants were semidominant to the wild-type allele. The 15 independently isolated mutants all fell into the same complementation group, defining a single gene, tpa-1. The gene tpa-1 mapped near the marker gene dpy-9 on chromosome IV.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0143-3334
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
783-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
A gene involved in action of tumor promoters is identified and mapped in Caenorhabditis elegans.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't