Linked Life Data

6860626

Source:http://linkedlifedata.com/resource/pubmed/id/6860626

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-8-11
pubmed:abstractText
The calcium and phosphorus concentrations in foetal tissue or the placental transfer of 45Ca and 32P, or both, were studied in fifty-five control or 1 alpha-hydroxycholecalciferol (1 alpha-(OH)D3)-treated (0.1 micrograms/kg body-weight per d for 12 d) ewes between 77 and 140 d of gestation. Treatment resulted in a significant increase in the concentration of Ca and P in foetal tissues at all stages of gestation except at 140 d when, it is suggested, foetal mineralization may approach a maximum value. This increase in Ca and P concentration in foetal tissues was associated with an increased placental transfer of Ca, though at 111 and 120 d gestation this increase was not significant. P transfer, which was only measured at 140 d gestation, was also significantly higher in treated animals. The concentrations of Ca and P in both maternal and foetal plasma were increased significantly by the 1 alpha-(OH)D3 treatment. Whereas the concentration of Ca in the plasma of foetuses was always greater than in their dams, the concentration of plasma P in treated animals, unlike controls, was lower in foetuses than dams. This suggests that the increased placental transfer of P, unlike that of Ca, may be a passive rather than an active process.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0007-1145
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
475-80
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
The effect of 1 alpha-hydroxycholecalciferol on the placental transfer of calcium and phosphate in sheep.
pubmed:publicationType
Journal Article