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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1976-8-23
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pubmed:abstractText |
The effect of phosvitin (1 g kg(-1), i.p.) on ecg changes induced in rats by a reduction of partial oxygen pressure in the respiratory mixture was studied. Phosphocreatine, phosphoserine, ATP and Na2HPO42H2O were also administered intraperitoneally for comparison. Phosvitin alone was found to prevent the hypoxia-induced T-wave changes (flattening or disappearance), which were also temporarily aggravated by injection of noradrenaline. As to the metabolic, hypoxia-induced myocardial changes, two hypotheses are discussed: a release of phosvitin phosphate radicals ready for immediate utilization or a drug action mediated via a membrane-bound intrinsic proteinkinase system.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-3573
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
127-32
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:6671-Animals,
pubmed-meshheading:6671-Anoxia,
pubmed-meshheading:6671-Blood Pressure,
pubmed-meshheading:6671-Egg Proteins,
pubmed-meshheading:6671-Electrocardiography,
pubmed-meshheading:6671-Heart Rate,
pubmed-meshheading:6671-Male,
pubmed-meshheading:6671-Myocardial Contraction,
pubmed-meshheading:6671-Norepinephrine,
pubmed-meshheading:6671-Oxygen Consumption,
pubmed-meshheading:6671-Phosvitin,
pubmed-meshheading:6671-Rats
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pubmed:year |
1976
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pubmed:articleTitle |
Effects of phosvitin on the ecg changes induced under hypoxia in the rat.
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pubmed:publicationType |
Journal Article
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