pubmed-article:6659148 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6659148 | lifeskim:mentions | umls-concept:C0028606 | lld:lifeskim |
pubmed-article:6659148 | lifeskim:mentions | umls-concept:C0025552 | lld:lifeskim |
pubmed-article:6659148 | lifeskim:mentions | umls-concept:C0175631 | lld:lifeskim |
pubmed-article:6659148 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
pubmed-article:6659148 | lifeskim:mentions | umls-concept:C2827662 | lld:lifeskim |
pubmed-article:6659148 | lifeskim:mentions | umls-concept:C1710236 | lld:lifeskim |
pubmed-article:6659148 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
pubmed-article:6659148 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
pubmed-article:6659148 | pubmed:issue | 2-3 | lld:pubmed |
pubmed-article:6659148 | pubmed:dateCreated | 1984-2-24 | lld:pubmed |
pubmed-article:6659148 | pubmed:abstractText | Unstained DNA has been directly imaged for the first time on a metallic substrate. Reproducible, three-dimensional images of molecular morphology following aqueous deposition onto tungsten have been obtained. The images confirm the importance of reducing surface tension forces during drying. Preadsorption of poly-l-lysine seems to improve image quality although optimum conditions are quite different than those reported in the TEM literature for insulating substrates. Our results suggest that poly-l-lysine should be preadsorbed as a neutral molecule at high pH. Following adsorption, the pH should be reduced in order to establish a net positive surface charge density. The presence of positive charges on a tungsten surface helps to preserve DNA morphology following adsorption from aqueous solution. | lld:pubmed |
pubmed-article:6659148 | pubmed:language | eng | lld:pubmed |
pubmed-article:6659148 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6659148 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6659148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6659148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6659148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6659148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6659148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6659148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6659148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6659148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6659148 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6659148 | pubmed:issn | 0304-3991 | lld:pubmed |
pubmed-article:6659148 | pubmed:author | pubmed-author:PanitzJ AJA | lld:pubmed |
pubmed-article:6659148 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6659148 | pubmed:volume | 11 | lld:pubmed |
pubmed-article:6659148 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6659148 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6659148 | pubmed:pagination | 161-6 | lld:pubmed |
pubmed-article:6659148 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:meshHeading | pubmed-meshheading:6659148-... | lld:pubmed |
pubmed-article:6659148 | pubmed:year | 1983 | lld:pubmed |
pubmed-article:6659148 | pubmed:articleTitle | Direct visualization of unstained nucleic acids on a metal substrate. | lld:pubmed |
pubmed-article:6659148 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6659148 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |