Linked Life Data

6651878

Source:http://linkedlifedata.com/resource/pubmed/id/6651878

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
1984-1-26
pubmed:abstractText
The effect of benserazide, an aromatic L-amino acid decarboxylase inhibitor, has been investigated simultaneously on the noradrenaline content of the pineal, hypothalamus and cerebral cortex of the rat. The dopamine concentration of the hypothalamus was investigated in the same animals. Benserazide had no effect on pineal noradrenaline content throughout the light phase and the early part of the dark phase but caused a drastic reduction in the latter part of the dark period. The drug had no significant effect on noradrenaline or dopamine contents of the hypothalamus. Benserazide treatment caused a large reduction in the noradrenaline content of the cerebral cortex throughout 24 hr. However, this effect is unlikely to be due to a differential penetration of benserazide into the brain areas as a similar degree of decarboxylase inhibition was observed in all three tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0006-2952
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3605-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Differential effect of benserazide on catecholamine concentrations in the rat pineal, cerebral cortex and hypothalamus.
pubmed:publicationType
Journal Article, Comparative Study