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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1984-6-13
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pubmed:abstractText |
The pupils of neonates often need to be dilated to examine the retina for retinopathy of prematurity and other disorders. It is known that low-weight infants (less than 1600 grams) are susceptible to systemic hypertension when 10% or 2.5% phenylephrine eye drops are used. To find the safest and best commercially available mydriatic agent in neonates, 30 low-weight infants were divided evenly into three groups. The drops tested were cyclopentolate 0.5% alone, cyclopentolate 0.5% plus mydriacyl 0.5%, and a combination drop of phenylephrine 1% and cyclopentolate 0.2%. There was no clinically significant effect of any of the drops on systolic blood pressure or pulse rate. The cyclopentolate and phenylephrine combination dilated the pupils by a mean of 2.8 mm which was statistically greater than the other groups (P less than 0.01) and had a longer duration of maximal dilation than the other drops (P less than 0.05).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cyclopentolate,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Mydriatics,
http://linkedlifedata.com/resource/pubmed/chemical/Phenylephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Tropicamide
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0161-6420
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
278-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6546977-Blood Pressure,
pubmed-meshheading:6546977-Cyclopentolate,
pubmed-meshheading:6546977-Drug Combinations,
pubmed-meshheading:6546977-Humans,
pubmed-meshheading:6546977-Infant, Low Birth Weight,
pubmed-meshheading:6546977-Infant, Newborn,
pubmed-meshheading:6546977-Mydriatics,
pubmed-meshheading:6546977-Phenylephrine,
pubmed-meshheading:6546977-Pulse,
pubmed-meshheading:6546977-Retinopathy of Prematurity,
pubmed-meshheading:6546977-Tropicamide
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pubmed:year |
1984
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pubmed:articleTitle |
A comparison of mydriatic eyedrops in low-weight infants.
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pubmed:publicationType |
Journal Article,
Comparative Study
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